Overview

Director, Patient Centered Outcomes (PCO) role at GSK.

Locations: Upper Providence, PA (GSK HQ) or Stevenage, UK. Hybrid 2-3 days per week. Additional flexible arrangements considered on a case-by-case basis.

Posted Date: Sep 30 2025

Job Purpose

As a Director of Patient-Centered Outcomes (PCO) you will apply technical expertise to plan and support evidence development strategies for Patient Reported Outcomes (PRO) / Clinical Outcome Assessment (COA) endpoints across GSK’s portfolio. The PCO team develops integrated evidence plans to ensure PRO/COA strategies support a patient-centric understanding of drug development across Respiratory, Immunology and Inflammation, Infectious Diseases, Vaccines and Oncology. Our mission is to deliver strong measurement science to capture the patient voice in demonstrating the value of our products to patients, physicians, payers, and regulators.

The team has educational backgrounds across PRO/COA disciplines and experience in pharmaceutical, regulatory, and academic settings. We work in a matrix environment with cross-functional partnership across Clinical Development, Regulatory Affairs, Biostatistics, Medical Affairs, Commercial and Patient Focused Development, and we engage with external initiatives exploring innovative PRO/COA approaches.

The PCO team focuses on the value of patient-centric outcomes across the portfolio, ensuring every clinical program has a well-characterized, innovative PRO/COA strategy defined early in development with plans to develop evidence supporting PRO/COA endpoints.

Key Responsibilities

• Define and oversee the execution of strategies for the development and implementation of PRO/COAs across GSK’s portfolio.
• Guide the development, validation, analysis, interpretation, and utilization of PRO/COA instruments in clinical trials and/or observational studies.
• Collaborate cross-functionally (e.g., clinical operations, biostatistics) to communicate the value of patient-centric endpoints and ensure PRO/COAs are appropriately implemented and described in SPAs, study reports, and publications.
• Support communications with regulatory bodies by developing targeted questions related to PRO/COA endpoints and identifying critical evidence for meetings to support patient-centric endpoint strategies.
• Contribute to external publications (e.g., abstracts and peer-reviewed manuscripts) presenting PRO-related results from trials and PRO development/validation studies.
• Maintain awareness of scientific and regulatory changes across GSK’s drug development programs.
• Pursue ongoing learning to adopt evolving methodologies and guidelines (including regulatory guidance) and communicate findings to relevant teams.

Qualifications

Basic Qualifications:

• Master’s or Doctoral degree in Psychology, Psychometrics, Social Sciences, Outcomes Research, Health services research, Public Health, Epidemiology, Pharmacy, or a closely related discipline.
• 7+ years of experience in a related role with demonstrated PRO/COA development and implementation experience in a consulting and/or pharmaceutical environment.
• Experience in pharmaceuticals, particularly in drug and vaccine development, with trial planning and execution experience.
• Experience with FDA Patient Focused Drug Development Guidance.
• Experience in planning and managing PRO development and validation projects.
• Experience in including COA endpoints in clinical trials and analyzing PRO data.
• Experience in managing internal stakeholders through to executive levels.
• Working knowledge of psychometric methods for PRO/COA validation.
• Familiarity with evolving PRO/COA methodologies and regulatory environment.

Preferred Qualifications:

• Understanding of healthcare markets and regulatory/reimbursement decision-making, especially global use of PRO data in drug/vaccine development.
• Strong verbal and written communication skills.

LI-GSK

Hybrid

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company focused on four therapeutic areas to impact health at scale: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases. We strive to create an environment where people can thrive and focus on what matters most, delivering for patients, shareholders and our people.

If you require accommodation or assistance to apply, contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service, or any basis prohibited by law.

Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses/agencies. All agencies must obtain prior written authorization before referring candidates to GSK.

Note: US-based applicants may have to report certain transfers of value under federal/state transparency requirements.

Seniority level

• Not Applicable

Employment type

• Full-time

Job function

• Other

Industries

• Pharmaceutical Manufacturing